"Good Morning, Mood Criminal. The Doctor will see you now."
The largest-ever meta-analysis of antidepressant trials appeared yesterday in the British Medical Journal. Researchers from the Cochrane Collaboration reviewed 70 trials (involving 18,526 subjects), to find that - counter to the initially-reported findings - antidepressants doubled the risk of suicide and aggression in subjects under 18. This risk had been misrepresented in the original study reports, the authors say, and suggest that the risks to adults may be similarly under-reported.
"Antidepressants don't work in children, that is pretty clear," said lead author Peter Gøtzsche. "In the randomised trials children say that they don't work for them, but they increase their risk of suicide ... What I get out of this colossal underreporting of suicides is that SSRIs likely increase suicides in all ages."