Thursday, November 29, 2012

Four Leading Antipsychotics Aren't Safe or Effective In Older Adults

Mad In America has;
Four Leading Antipsychotics Aren't Safe or Effective In Older Adults

"A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the University of Iowa, comparing the effects of Abilify, Zyprexa, Seroquel and Risperdal on 332 patients over the age of 40, finds that “While there were a few significant differences among the four drugs, the overall risk-benefit ratio for the AAPs in patients over age 40 was not favorable, irrespective of diagnosis and drug.” Results were released online yesterday by the Journal of Clinical Psychiatry.
Jin, Hua., Shih, P., Golshan, S., et al; Comparison of Longer-Term Safety and Effectiveness of 4 Atypical Antipsychotics in Patients Over Age 40: A Trial Using Equipoise-Stratified Randomization. Journal of Clinical Psychiatry. Online November 27, 2012

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